Vacation planning

I always feel like summer is winding down just as it begins. It feels so short. We only have two weeks left at home before we head to Las Vegas for a 10 day vacation and then August is pretty much over. Sure, our vaca will be fun, but relaxing definitely not. We will spend part of the trip being tourists with Ben's family and then the other half with my grandparents. It will be so nice to see them as well as my sister, nephews, and niece. I must admit, I am a bit worried about the 3 hour time change. I am not sure how to handle it. We leave at 7pm from Boston, we have a lay over in Chicago and then we arrive in Las Vegas at midnight. My hopes are that she sleeps like a champ this trip and really enjoys the new surroundings and new people. Are my hopes too high? Any tips for the layover?